Kindon, Nicholas D.: search on Z-Library

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1

Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C–C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase δ (PI3Kδ) Inhibitors

Schwehm, Carolin, Kellam, Barrie, Garces, Aimie E., Hill, Stephen J., Kindon, Nicholas D., Bradshaw, Tracey D., Li, Jin, Macdonald, Simon J. F., Rowedder, James E., Stoddart, Leigh A., Stocks, Michael

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 3.06 MB

english, 2017

2

Antagonists of the Platelet P 2T Receptor: A Novel Approach to Antithrombotic Therapy

Ingall, Anthony H., Dixon, John, Bailey, Andrew, Coombs, Mandy E., Cox, David, McInally, Judith I., Hunt, Simon F., Kindon, Nicholas D., Teobald, Barry J., Willis, Paul A., Humphries, Robert G., Leff,

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 137 KB

english, 1999

3

Synthesis and C -Alkylation of Hindered Aldehyde Enamines

Hodgson, David M., Bray, Christopher D., Kindon, Nicholas D., Reynolds, Nigel J., Coote, Steven J., Um, Joann M., Houk, K. N.

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 470 KB

english, 2009

4

Hit-to-Lead studies: The discovery of potent, orally bioavailable triazolethiol CXCR2 receptor antagonists

Andrew Baxter, Colin Bennion, Janice Bent, Kerry Boden, Steve Brough, Anne Cooper, Elizabeth Kinchin, Nicholas Kindon, Tom McInally, Mike Mortimore, Bryan Roberts, John Unitt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 171 KB

english, 2003

5

Subtype-selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A2A Receptor

Comeo, Eleonora, Kindon, Nicholas D., Soave, Mark, Stoddart, Leigh A., Kilpatrick, Laura, Scammells, Peter J., Hill, Stephen John, Kellam, Barrie

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 2.23 MB

english, 2019

6

The discovery of new spirocyclic muscarinic M3 antagonists

Michael J. Stocks, Lilian Alcaraz, Andrew Bailey, Keith Bowers, David Donald, Helen Edwards, Fraser Hunt, Nicholas Kindon, Garry Pairaudeau, Jill Theaker, Daniel J. Warner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 502 KB

english, 2010

7

The discovery of AZD-2098 and AZD-1678, two potent and bioavailable CCR4 receptor antagonists.

Kindon, Nicholas D., Andrews, Glen, Baxter, Andrew, Cheshire, David, Hemsley, Paul, Johnson, Timothy, Liu, Yu-Zhen, McGinnity, Dermot, McHale, Mark, Mete, Antonio, Reuberson, James, Roberts, Bryan, St

Journal:

ACS Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 418 KB

english, 2017

8

Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells

Stoddart, Leigh A., Kindon, Nicholas D., Otun, Omolade, Harwood, Clare R., Patera, Foteini, Veprintsev, Dmitry B., Woolard, Jeanette, Briddon, Stephen J., Franks, Hester A., Hill, Stephen J., Kellam,

Journal:

Communications Biology

Year:

2020

File:

PDF, 1.49 MB

2020

9

Diastereomer-Dependent Substrate Reduction Properties of a Dinitrogenase Containing 1-Fluorohomocitrate in the Iron-Molybdenum Cofactor

Mark S. Madden, Nicholas D. Kindon, Paul W. Ludden and Vinod K. Shah

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.39 MB

english, 1990

10

Diastereoselectivity in the SE2? reaction of chiral pentadienylsilanes: a test for the relative importance of steric and electronic effects

Fleming, Ian, Jones, Graeme R., Kindon, Nicholas D., Landais, Yannick, Leslie, Colin P., Morgan, Ian T., Peukert, Stefan, Sarkar, Achintya K.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1996

Language:

english

File:

PDF, 4.31 MB

english, 1996

11

2-Ene-1,4-diols by Dimerization of Terminal Epoxides Using Hindered Lithium Amides.

David M. Hodgson, Christopher D. Bray, Nicholas D. Kindon

Journal:

Year:

2005

File:

PDF, 19 KB

2005

12

The stereochemistry of an SE2″ reaction of a chiral dienylmethylsilane

Ian Fleming, Nicholas D. Kindon, Achintya K. Sarkar

Journal:

Tetrahedron Letters

Year:

1987

Language:

english

File:

PDF, 281 KB

english, 1987

13

Synthesis and Evaluation of the first Fluorescent Antagonists of the Human P2Y 2 Receptor based on AR-C118925

Conroy, Sean, Kindon, Nicholas D., Glenn, Jacqueline, Stoddart, Leigh A., Lewis, Richard James, Hill, Stephen J., Kellam, Barrie, Stocks, Michael John

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.02 MB

english, 2018

14

Drug-like antagonists of P2Y receptors - from lead identification to drug development

Conroy, Sean, Kindon, Nicholas, Kellam, Barrie, Stocks, Michael John

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.59 MB

english, 2016

15

Subtype-selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A2A Receptor

Comeo, Eleonora, Kindon, Nicholas D., Soave, Mark, Stoddart, Leigh A., Kilpatrick, Laura, Scammells, Peter J., Hill, Stephen John, Kellam, Barrie

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 2.23 MB

2019

16

Enamines from Terminal Epoxides and Hindered Lithium Amides

Hodgson, David M., Bray, Christopher D., Kindon, Nicholas D.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 54 KB

english, 2004

17

Diastereoselectivity in the preparation of ?-silylesters from ??-unsaturated esters and amides attached to chiral auxiliaries

Fleming, Ian, Kindon, Nicholas D.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1987

Language:

english

File:

PDF, 243 KB

english, 1987

18

Enamines from Terminal Epoxides and Hindered Lithium Amides.

David M. Hodgson, Christopher D. Bray, Nicholas D. Kindon

Journal:

Year:

2004

File:

PDF, 37 KB

2004

19

From libraries to candidate: The discovery of new ultra long-acting dibasic β2-adrenoceptor agonists

Lilian Alcaraz, Andrew Bailey, Elaine Cadogan, Stephen Connolly, Robert Jewell, Stephen Jordan, Nicholas Kindon, Andrew Lister, Mandy Lawson, Alexander Mullen, Ian Dainty, David Nicholls, Stuart Paine

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 839 KB

english, 2012

20

Correction to Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y 2 Receptor Based on AR-C118925

Conroy, Sean, Kindon, Nicholas D., Glenn, Jacqueline, Stoddart, Leigh A., Lewis, Richard J., Hill, Stephen J., Kellam, Barrie, Stocks, Michael J.

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 203 KB

english, 2018

21

Diastereoselectivity in the preparation of ?-silyl esters from ??-unsaturated esters and amides attached to chiral auxiliaries

Fleming, Ian, Kindon, Nicholas D.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1995

Language:

english

File:

PDF, 1.58 MB

english, 1995

22

From UTP to AR-C118925, the discovery of a potent non nucleotide antagonist of the P2Y 2 receptor

Kindon, Nicholas, Davis, Andrew, Dougall, Iain, Dixon, John, Johnson, Timothy, Walters, Iain, Thom, Steve, McKechnie, Kenneth, Meghani, Premji, Stocks, Michael J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 782 KB

english, 2017

23

2-Ene-1,4-diols by Dimerization of Terminal Epoxides using Hindered Lithium Amides

Hodgson, David M., Bray, Christopher D., Kindon, Nicholas D.

Journal:

Organic Letters

Year:

2005

Language:

english

File:

PDF, 1.21 MB

english, 2005

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